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feline odontoclastic resorptive lesion : ウィキペディア英語版 | feline odontoclastic resorptive lesion
Feline Tooth Resorption (TR) is a syndrome in cats characterized by resorption of the tooth by odontoclasts, cells similar to osteoclasts. TR has also been called "feline odontoclastic resorption lesion" (FORL), neck lesion, cervical neck lesion, cervical line erosion, feline caries, or feline cavity. It is one of the most common diseases of domestic cats, affecting up to two-thirds.〔van Wessum R, Harvey CE, Hennet P. "Feline dental resorptive lesions. Prevalence patterns." ''Vet Clin North Am Small Anim Pract.'' 1992 Nov;22(6):1405-16. PMID 1455579.〕 TRs have been seen more recently in the history of feline medicine due to the advancing ages of cats, but 800-year-old cat skeletons have shown evidence of this disease. Purebred cats, especially Siamese and Persians, may be more susceptible. TRs appear as erosions of the surface of the tooth at the gingival border. They are often covered with calculus or gingival tissue. It is a progressive disease, usually starting with loss of cementum and dentin and leading to penetration of the pulp cavity. Resorption continues up the dentinal tubules into the tooth crown. The enamel is also resorbed or undermined to the point of tooth fracture. Resorbed cementum and dentin is replaced with bone-like tissue. ==Clinical signs==
Clinical signs of TRs are often minimal since the discomfort can be minor. However, some authors have described discomfort while chewing, anorexia, dehydration, weight loss, and tooth fracture. The lower third premolar is the most commonly affected tooth.〔
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